Medical Spa Denver CO Lady Smiling

Laugh lines, also called marionette lines or nasolabial folds (if you want to get medical), are those grooves, creases or folds that run vertically from the corners of the mouth down to the chin. Ironically, laugh lines are not caused by years of laughing. As you age, collagen and elastin (two crucial skin components to younger-looking skin) begin to break down. Your skin loses its fullness and its ability to bounce back into place, leading to wrinkles and creases like laugh lines. It’s absolutely nothing to laugh about. But with Restylane Refyne, you can feel more than hopeful.


Restylane Refyne can help put the happy back on your face. Restylane Refyne injections can plump your skin, improve collagen production, and bring moisture to the area, literally “filling” in those laugh lines. This can help restore a more natural look to your face while maintaining your facial expressions. And with Restylane Refyne, one of those expressions could be “ecstatic”.


While we’re talking about natural, the natural place to get Restylane Refyne injections in the Denver area is Adore Aesthetix. When it comes to fillers like Restylane Refyne, there’s an art to doing it right, and no one approaches things with a more artistic eye than Sarah Kurts, board-certified physician assistant. With Restylane Lyft, she uses a less is more approach that is unique to each patient. So you’ll never get a look that is overdone and unnatural. Because no one’s best look is not looking like themselves.

Restylane Refyne FAQS

NEW Restylane Refyne integrates with your skin to help smooth out the lines that run alongside the corners of your mouth (nasolabial folds and marionette lines)* and the flexibility you need for natural-looking movement and expressions.

NEW Restylane Refyne & NEW Restylane Defyne: In a clinical study of subjects treated for laugh lines with Restylane Refyne and Restylane Defyne, investigators reported improvement in the appearance of wrinkles for up to 12 months in the majority of patients. Using the Wrinkle Severity Rating Scale (WSRS), a validated 5-point measure of the size and depth of the wrinkles, with grade 1 defined as absence of wrinkles and grade 5 as extremely deep and long wrinkles, investigators reported that 79% of Restylane Refyne subjects and 77% of Restylane Defyne subjects had at least a 1-grade improvement on the WSRS after 6 weeks. Subjects also performed self-assessments (SSA) of wrinkle severity, with most reporting at least a 1-grade improvement in SSA scores with Restylane Refyne and with Restylane Defyne after 6 weeks.

Depending on your volume needs, most Restylane treatment appointments last less than an hour and begin to work almost immediately by adding volume to smooth away wrinkles. A clear gel formulation of hyaluronic acid, Restylane products act like your body’s own hyaluronic acid (and eventually break down naturally). Each Restylane product is designed for a specific purpose.

After your treatment, you may experience side effects, such as swelling, redness, pain, bruising, headache and itching at the injection site and tenderness. These are typically mild in severity and normally last less than 7 days in nasolabial folds and less than 14-18 days in lips. Patients should be limited to 6.0 mL per treatment of moderate to severe facial wrinkles and folds. Swelling may be more likely in patients under 36 years, and bruising may be more likely in patients over 35 years.

Initial Restylane treatments are usually complete in one or two sessions, as needed. Depending on your individual body chemistry, you will work with your specialist to determine a maintenance schedule. Talk to your physician or healthcare professional about your individual needs.

The Restylane family of products should not be used by people who:

  • Are pregnant, breastfeeding, or under 18 years for nasolabial folds and under 22 years for lips (Restylane and Restylane Silk only)
  • Have recently used drugs that thin the blood or prevent clotting
  • Have had previous bad allergies, particularly to microorganisms known as gram-positive bacteria
  • Have serious allergies to drugs that have previously required in-hospital treatment
  • Have bleeding disorders
  • Have a known allergy to lidocaine, if using Restylane Lyft, Restylane, Restylane Refyne or Restylane Defyne

Schedule an



8:30am - 4:30pm

8:30am - 4:30pm

8:30am - 4:30pm

8:30am - 4:30pm

8:30am - 4:30pm


Adore Aesthetix
1221 South Clarkson Street #300
Denver, CO 80210
(303) 513-0196