Medical Spa Denver CO Lady Smiling

Age can have a disheartening effect on your entire body, but it is probably most obvious on your face. Because every day, in every way, you have to get out there and face the world. As the body ages, its supply of collagen gradually breaks down, which diminishes facial volume and elasticity. This loss of elasticity and volume makes facial wrinkles and folds appear more prominent. Your face takes on the look of a permanent frown, making you look sad, tired or angry, even when you’re not. Not funny. But there is something to smile about; Restylane Defyne.


With Restylane Defyne, you can look like you did when you were younger. You can look more energized and more refreshed. Restylane Defyne is as effective as Restylane Refyne, but Restylane Defyne is more suitable for certain applications due to the particular muscle and skin movements of each area.

Restylane Defyne is designed to help maintain a natural look through a range of facial expressions while smoothing out deeper lines and wrinkles in the skin, and like Restylane Refyne, Restylane Defyne is long-lasting, up to 12 months.


Everyone at Adore Aesthetix understands how deep furrows, wrinkles, and folds can also have a serious negative effect on your self-confidence. This is just one of the many reasons patients choose Adore Aesthetix over anyone else in the Denver area. All our treatments, like Restylane Defyne, are medically supervised, performed by Sarah Kurts, board-certified physician assistant. Our Restylane Defyne treatments in Denver are all customized to your unique needs and concerns. Before we do anything, we spend time getting to know you and understand your desired goals. This allows us to deliver results that not only meet our clients’ expectations, but exceed them. It’s your face. Why trust it to anyone else?

Medical Spa Denver CO Restylane Defyne Before and After

Restylane Defyne FAQS

NEW Restylane Defyne is designed to act like your body’s own hyaluronic acid to help smooth out deeper lines around your mouth (nasolabial folds and marionette lines) while letting you look more natural through a range of facial expressions.

NEW Restylane Refyne & NEW Restylane Defyne: In a clinical study of subjects treated for laugh lines with Restylane Refyne and Restylane Defyne, investigators reported improvement in the appearance of wrinkles for up to 12 months in the majority of patients. Using the Wrinkle Severity Rating Scale (WSRS), a validated 5-point measure of the size and depth of the wrinkles, with grade 1 defined as absence of wrinkles and grade 5 as extremely deep and long wrinkles, investigators reported that 79% of Restylane Refyne subjects and 77% of Restylane Defyne subjects had at least a 1-grade improvement on the WSRS after 6 weeks. Subjects also performed self-assessments (SSA) of wrinkle severity, with most reporting at least a 1-grade improvement in SSA scores with Restylane Refyne and with Restylane Defyne after 6 weeks.

Depending on your volume needs, most Restylane treatment appointments last less than an hour and begin to work almost immediately by adding volume to smooth away wrinkles. A clear gel formulation of hyaluronic acid, Restylane products act like your body’s own hyaluronic acid (and eventually break down naturally). Each Restylane product is designed for a specific purpose.

After your treatment, you may experience side effects, such as swelling, redness, pain, bruising, headache and itching at the injection site and tenderness. These are typically mild in severity and normally last less than 7 days in nasolabial folds and less than 14-18 days in lips. Patients should be limited to 6.0 mL per treatment of moderate to severe facial wrinkles and folds. Swelling may be more likely in patients under 36 years, and bruising may be more likely in patients over 35 years.

Initial Restylane treatments are usually complete in one or two sessions, as needed. Depending on your individual body chemistry, you will work with your specialist to determine a maintenance schedule. Talk to your physician or healthcare professional about your individual needs.

The Restylane family of products should not be used by people who:

  • Are pregnant, breastfeeding, or under 18 years for nasolabial folds and under 22 years for lips (Restylane and Restylane Silk only)
  • Have recently used drugs that thin the blood or prevent clotting
  • Have had previous bad allergies, particularly to microorganisms known as gram-positive bacteria
  • Have serious allergies to drugs that have previously required in-hospital treatment
  • Have bleeding disorders
  • Have a known allergy to lidocaine, if using Restylane Lyft, Restylane, Restylane Refyne or Restylane Defyne

Schedule an



8:30am - 4:30pm

8:30am - 4:30pm

8:30am - 4:30pm

8:30am - 4:30pm

8:30am - 4:30pm


Adore Aesthetix
1221 South Clarkson Street #300
Denver, CO 80210
(303) 513-0196